Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 1
Additions to Alkenes, Alkynes, and Carbonyl Compounds| By: | van Leeuwen, P. W. N. M. |
| Publisher: | Thieme Medical Publishers Inc. |
| Print ISBN: | 9783131707611 |
| eText ISBN: | 9783131765215 |
| Edition: | 1 |
| Copyright: | 2014 |
| Format: | Page Fidelity |
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The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.